منابع مشابه
Growth Hormone-Releasing Hormone in Diabetes
Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland. In addition, GHRH is an important regulator of cellular functions in many cells and organs. Expression of GHRH G-Protein Coupled Receptor (GHRHR) has been demonstrated in different peripheral tissues and cell types, including pancreatic isl...
متن کاملGrowth hormone-releasing peptides.
Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans. The GHRP receptor has recently been cloned and, interestingly, it do...
متن کاملGrowth hormone releasing hormone or growth hormone treatment in growth hormone insufficiency?
Sixteen prepubertal children who were insufficient for growth hormone were treated with growth hormone releasing hormone (GHRH) 1-40 and GHRH 1-29 for a mean time of nine months (range 6-12 months) with each peptide. Eleven children received GHRH 1-40 in four subcutaneous nocturnal pulses (dose 4-8 micrograms/kg/day) and eight (three of whom were also treated with GHRH 1-40) received GHRH 1-29 ...
متن کاملGrowth hormone responses to growth-hormone-releasing hormone and thyrotropin-releasing hormone in diabetic patients with and without retinopathy.
Growth hormone (GH) responses to growth-hormone-releasing hormone (GRH) and thyrotropin-releasing hormone (TRH) were studied in 17 diabetic patients. Ten patients (group 1) had retinopathy corresponding to stage III-V (Scott's classification), and the remaining seven patients (group 2) had no retinopathy despite longer duration of diabetes in comparison with the patients in group 1. There were ...
متن کاملبررسی چند شکلی ژنتیکی و فراوانی آللی جایگاه ژنی GHRH (Growth-hormone-releasing hormone) در گاوهای سرابی ایران
انتخاب حیوان بر اساس نشانگرهای مولکولی یکی از جدیدترین روشهای اصلاحی است که میتواند باعث بهبود صحت پیشبینی و پاسخ به انتخاب شود. GHRH (Growth-hormone-releasing hormone) یکیازژنهایبرگزیدهبرایاستراتژیهایانتخاببراساسمارکرمیباشد.براساسگزارشاتموجود، چندشکلیهایژن بهطورمعنیداریباصفاتاجزایشیروتولیدآنارتباطدارد. به منظور بررسی چندشکلی (پلیمورفیسم) مکان ژنی GHRH در نژاد سرابی، از 112 رأس گاو ...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1985
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.60.5.405